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Effects of Glucagon Like Peptide-1 Receptor Agonists on Endocrine Metabolism Interestingly, GLP-1RAs not only exert a protective effect on the nervous and cardiovascular systems, but also exhibit a regulatory effect on metabolism

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At the same time, they require strict adherence to dosing instructions and thoughtful counseling

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But Kim found that, if patients need to be on GLP-1 drugs indefinitely to achieve and maintain weight loss, their expense outweighs the economic benefit of avoiding obesity-related problems

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