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(4) study design: RCT published in full text

As far as the three MACE components are concerned, the use of GLP-1RA was associated with 13% reduced risk of cardiovascular mortality (HR = 0.87, Fig

In human studies , ginseng did seem to improve blood sugar control in people with diabetes, but larger and longer studies are needed

Moreover, A double-blind study of patients with T2DM treated with metformin led to significant changes in the relative abundance of more than 80 bacterial species compared with placebo after 4 months, in which an increase in Escherichia and Akkermansia muciniphila and a decrease in Intestinibacter were also observed, whereas most of the changes with placebo occurred in phylum Firmicutes and phylum Proteobacteria (Wu et al., 2017)