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Seo MK, Jeong S, Seog DH, Lee JA, Lee JH, Lee Y, et al

Location: Indianapolis, IndianaWarning Letter Date: September 9, 2025FDA Department Issuing Warning: Center for Drug Evaluation and Research (CDER)Type of Warning: False & Misleading Claims/Misbranded DrugsSubject of Violation: An Oprah Special: Shame, Blame, and the Weight Loss Revolution, regarding Zepbound (tirzepatide) and Mounjaro (tirzepatide)FDA Warning: In the program, which aired on television in 2024 and until recently was available continuously on the ABC website and through various streaming services, Eli Lilly promoted Mounjaro and Zepbound in a manner that failed to present the serious risks of these drug products in a truthful and nonmisleading manner, despite FDAs prior correspondence (advisory comments dated June 13, 2022 and June 21, 2022)

Here, we discuss results from Wave 12, conducted in February 2025

Dulaglutide (Trulicity) Exenatide (Byette) Exenatide extended-release (Bydureon) Liraglutide (Victoza) used for obesity Lixisenatide (Adlyxin) Semaglutide injection (Ozempic) used for obesity Semaglutide tablets (Rybelsus) used for obesity Tirzepatide (Mounjaro) a dual GLP-1/GIP receptor agonist If youre looking for how to lose weight without exercise and diet, GLP-1 agonist medications for type 2 diabetics and those with obesity might be something your doctor recommends to you

Disruption of glucagonlike peptide 1 signaling in Sim1 neurons reduces physiological and behavioral reactivity to acute and chronic stress

Studies suggest that the urine color is due to abnormal protein or sugar, as well as high numbers of cellular casts, and red and white blood cells
