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Both GIP and GLP-1 agonists are hormones naturally produced in our gastrointestinal system. Quinones says some people may experience more weight loss on Zepbound, including people not responding to Wegovy

But since Ozempic contains the identical active ingredient and produces similar results, many doctors prescribe it off-label for weight management

Some clinicians prescribe microdose protocols as low as 0.10.15 mg to further minimize early side effects, though 0.25 mg is the most common entry point
