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PK evaluation of unfused albumin variants and GLP-1 albumin fusions following IV injection was performed twice with four or five mice per test article

Antibody formation occurs in some patients, particularly with exenatide, though this rarely has clinical significance

6 This involvement of incretin hormones in people with type 2 diabetes contributed to the development of GLP-1 and GLP-1/GIP RAs, which mimic the naturally occurring incretin hormones

[DOI] [PubMed] [Google Scholar] 11.Drucker DJ

Cardioprotective and Vasodilatory Actions of Glucagon-like Peptide 1 Receptor Are Mediated through Both Glucagon-like Peptide 1 Receptor-dependent and -independent Pathways
