gaining weight on tirzepatide reddit :( : r/tirzepatidecompound Why Am I Gaining Weight
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At 6 months: Subcutaneous group: mean IGF-1 increase of 22%, body composition improvement (lean mass +2.1 kg, fat mass -1.8 kg), sleep quality improvement in 67% of patients Sublingual group: mean IGF-1 increase of 6%, body composition improvement (lean mass +0.4 kg, fat mass -0.6 kg), sleep quality improvement in 31% of patients The subcutaneous group showed statistically significant improvements across all endpoints

Glucagon-like peptide 1 (GLP-1) secretion and plasma dipeptidyl peptidase IV (DPP-IV) activity in morbidly obese patients undergoing biliopancreatic diversion
Tirzepatide doesn't require fasting

This delayed gastric emptying leads to prolonged feelings of fullness and reduced appetite, ultimately contributing to weight loss

individual complications
