![glp 1 monoclonal antibody Glutazumab, a novel long-lasting GLP-1/anti-GLP-1R fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sites Anti-GLP-1 antibody [4F3] (ab23472) |](https://ars.els-cdn.com/content/image/1-s2.0-S0006295218300297-fx1.jpg)
glp 1 monoclonal antibody Glutazumab, a novel long-lasting GLP-1/anti-GLP-1R fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sites Anti-GLP-1 antibody [4F3] (ab23472) |
Description
Following secretion, PYY is rapidly cleaved by dipeptidyl peptidase-4 (DPP-4) to its active form (PYY 3-36) acting on neuropeptide Y receptor type 2 (Y2R)
![glp 1 monoclonal antibody Glutazumab, a novel long-lasting GLP-1/anti-GLP-1R fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sites Anti-GLP-1 antibody [4F3] (ab23472) |](https://content.abcam.com/products/images/glp-1-antibody-4f3-ab23472--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img116323.jpg)
Why GLP-1 Needs Special Care When Youre On the Move At home, storing GLP-1 is simple and predictable
Sci Rep (2019) 9:111
![glp 1 monoclonal antibody Glutazumab, a novel long-lasting GLP-1/anti-GLP-1R fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sites Anti-GLP-1 antibody [4F3] (ab23472) |](https://content.abcam.com/products/images/glp-1-antibody-epr4042-1-ab108443--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img68146.jpg)
Skibicka et al., 2011
The reality is likely more nuanced
![glp 1 monoclonal antibody Glutazumab, a novel long-lasting GLP-1/anti-GLP-1R fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sites Anti-GLP-1 antibody [4F3] (ab23472) |](https://www.news-medical.net/images/appnotes/ImageForAppNote_5258_17259570697022080.png)
However, an oral version of the drug (aka the Wegovy pill ) is awaiting FDA approval and may be given the green light soon
![glp 1 monoclonal antibody Glutazumab, a novel long-lasting GLP-1/anti-GLP-1R fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sites Anti-GLP-1 antibody [4F3] (ab23472) |](https://assets.fishersci.com/TFS-Assets/BID/product-images/primary-antibody-image.jpg-650.jpg)
