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In the future, we look forward to the clinical research evidence of small-molecule GLP-1RA intervening in ischemic stroke or T2D complicated by ischemic stroke

When lean mass declines, the body burns fewer calories at rest, which increases the risk of weight regain over time

doi: 10.1530/jme-13-0200 45 KimS-HParkM-J

10.1007/s00213-025-06834-7

In a recent review of GLP-1 RA patient preferences, important attributes driving patient choice included dose frequency, device characteristics (including type of device and needle size), change in HbA1c, and adverse event profile [124]

In short: healthy weight loss requires sufficient calories, adequate protein, and mechanical stimulus