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Conclusion: GLP-1RAs appear to reduce pain in patients with knee osteoarthritis, likely through weight reduction

In the SURMOUNT trials, anxiety rates were actually numerically lower in the tirzepatide group compared to placebo

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Association of sex, age, and NSAIDs with responsiveness to GLP1-M treatment NSAIDs, which are among the most commonly used medications for treating various medical conditions, have a complex relationship with glucose metabolism

Zhang, K., Hooper, W., Harkness, L., & Ghassemi, A

The ENS also expresses GLP-1 receptors 39 , but the local effects of GLP-1 could not be proven because GLP-1RA was ineffective in our studies in Ussing chamber experiments