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doi: 10.1080/00325481.2021.2002616

Inducible reporter assays, especially luciferase reporters, which are linked to the activation of specific signaling pathways for example by the GIP receptor, provide a reliable measurement of the inhibitory or activating effect of substances on diabetes-associated cell signaling pathways (Fig

Bergmann NC, Lund A, Gasbjerg LS, Meessen ECE, Andersen MM, Bergmann S, Hartmann B, Holst JJ, Jessen L, Christensen MB, et al

Tirzepatide is prescribed in milligrams

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But fair comparison requires acknowledging the differences in trial design, duration, and population that make direct head-to-head claims imprecise
