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Retatrutide is a next-generation synthetic peptide acting as a triple receptor agonist, simultaneously targeting GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors

Abstract The development oftirzepatide, a first in class dual glucose dependent insulinotropic polypeptide andglucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management oftype 2 diabetesandobesity

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GLP-1 drugs have not shown as strong an uptake in Europe as in the US