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Pumping and dumping would unnecessarily waste breast milk without providing additional safety

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1 that it was discontinuing phase 3 clinical trials of the twice-daily version due to high rates of adverse side effects

The CVOT of oral semaglutide in people with type 2 diabetes and established CVD, chronic kidney disease (CKD) or both demonstrated a significant reduction in MACE compared with placebo (McGuire et al, 2025)

Mitoxantrone exerts its therapeutic effect in MS through the inhibition of proliferation of B and T lymphocytes and macrophages.Reference Morrissey, Le Page and Edan 38 In addition, several other immunosuppressive effects have been described, such as decreased secretion of IFN- , tumor necrosis factor-, and interleukin (IL)-2.Reference Morrissey, Le Page and Edan 38 A full course of mitoxantrone treatment can stabilize patients with aggressive MS for 5 years or more.Reference Le Page, Leray and Taurin 39 However, due to its long-term safety concern, lifetime exposure to mitoxantrone is limited.Reference Edan, Comi and Le Page 40 If maximal lifetime doses are reached, patients may require maintenance therapy with a DMT

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