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Trials will therefore require structured support slow titration, proactive side-effect management, nutritional and exercise guidance, and caregiver involvement to prevent dilution of efficacy signals

- Medical history: gather family history, pregnancy plans, diabetes status and current medications

Maintaining healthy habits developed during treatment helps minimise regain

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Klinic caters to adults with a BMI over 30 or 27 if accompanied by a weight-related condition like heart disease or obstructive sleep apnea