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We also confirmed the effect of GLP-1R on microglial activation in lipopolysaccharide-treated BV-2 microglia

This causes an increase in insulin production in the pancreas
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Bifidobacterium bifidum Ameliorates DSS-induced colitis in mice by regulating AHR/NRF2/NLRP3 inflammasome pathways through Indole-3-lactic acid production

The adequate management of GI AEs would potentially improve a patients experience while undergoing treatment with GLP-1 RA, preventing discontinuations secondary to GI AEs
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