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That said, the current work greatly advances our understanding of how bacterial signalling in the gut can both induce and also curtail intestinal inflammation, and reveals an exciting role for the gut hormone GLP-1 as a potential therapeutic target in the regulation of inflammatory diseases of the intestine

Studies show that 40 to 85 percent of people taking standard doses of GLP-1s have side effects, most often gastrointestinal troubles like nausea and vomiting

As a clinician, Tschp had become incredibly frustrated by the lack of an effective treatment for patients he saw with obesity

Keep out of reach of children under 18

Treatment Options at Gentle Patches Gentle Patches markets its GLP-1 patch as a weight-loss aid, but it does not contain any actual GLP-1 drugs, like semaglutide or tirzepatide

Novo Nordisks oral Wegovy, approved in December 2025, was the first oral GLP-1 to hit the obesity market