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Combining all three targets allows for synergistic metabolic benefits , while GLP-1 and GIP help buffer the blood sugarraising effect of glucagon [7]
Taranto-Montemurro L, Sands SA, Edwards BA, et al

Compounded semaglutide is often used as a weight loss medication
Oral Medications: Such as metformin, sulfonylureas, and SGLT2 inhibitors, with varying efficacy (usually reducing HbA1c by 0.5% to 1.5%)