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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have redefined the management of obesity and type 2 diabetes mellitus, producing sustained and clinically meaningful reductions in total body weight alongside significant cardiometabolic benefits

P.et al (2015)

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Through mimicking the GLP-1 hormone in charge of triggering insulin, slowing digestion and appetite, these medications extend the hormones effects to induce notable fullness long after eating

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Semaglutide and tirzepatide are synthetic receptor agonists, meaning they bind to these same receptors and activate them continuously rather than just after meals
