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Description
Methods We investigated the metabolic and mechanistic effects of combining semaglutide (GLP-1RA) with Akkermansia muciniphila 11 (Akk11) in db/db mice, a model of T2D-associated MASLD
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GLP-1 RAs showed several adverse gastrointestinal effects in non-diabetic patients with overweight or obesity

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Surprisingly, semaglutide had no discernible effect on the functionality of the somatotropic axis in malnourished mice