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Nausea and reduced appetite are among the most frequently reported side effects of GLP-1 medications, particularly during the initial weeks of treatment or following dose increases

[86] The mechanism underlying these neurological effects may relate to ondansetrons actions on central nervous system serotonin receptors

These include: Nausea, vomiting, and diarrhea Stomach pain and constipation Heartburn and belching Your body needs time to adjust to the medication, which causes these digestive issues

This difference stems from how insurers classify these drugs - Wegovy is often labeled as a lifestyle drug for weight loss, while Ozempic is approved for treating type 2 diabetes, making it more likely to be covered

After this adjustment period, you can gradually reintroduce richer foods, spices, and normal portion sizesthough semaglutide's appetite-suppressing effect means your natural interest in large meals has already changed

Currently uncertain