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09/18/24 Kisqali (ribociclib) New indication September 17, 2024 - Novartis announced the FDA approval of Kisqali (ribociclib), in combination with an aromatase inhibitor for the adjuvant treatment of adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative stage II and III early breast cancer at high risk of recurrence

This combination works primarily in the brain, reducing cravings and the pleasure response to food rather than creating physical feelings of fullness

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Three major trials have shown reduced kidney events, slower eGFR decline, and significant improvements in markers of kidney damage