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Activation of microglia in the trigeminal nucleus caudalis (TNC) contributes to this progression

Eli Lilly, makers of weight loss injection Zepbound, could soon be making its GLP-1 drug in pill form.

Importantly, large-scale randomized trials, meta-analyses, and observational studies suggest that GLP-1RAs do not significantly increase AKI risk and may even confer renal benefits in high-risk populations

The FDA has granted accelerated approval of Wegovy (semaglutide) for adults with moderate to advanced metabolic dysfunction-associated steatohepatitis (MASH)

Understanding the difference between appetite-suppressing drug classes helps patients and providers choose the most appropriate treatment based on individual physiology, comorbidities, and clinical response patterns