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Importantly, GLP-1 therapies have not been associated with an increased risk of pancreatitis or thyroid cancer in clinical trials

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Among the 3,532 participants in the FLOW trial, 19.2% (678 individuals) had heart failure at baseline, with 47.9% classified as having HFpEF, 18.1% as having heart failure with reduced ejection fraction (HFrEF), and 33.9% with unknown status

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She also laments the current limited access to these medications in Brazil, noting that, From a clinical standpoint, broader affordability would represent a major step forward in expanding access to evidence-based obesity and diabetes treatments. For now, she says the message for clinicians is clear: GLP-1RAs are an effective option for managing weight gain and metabolic complications in patients with psychiatric disorders without serious adverse events

The concentrated option keeps draw volumes small, which suits anyone who finds large-volume draws awkward