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Given the eminent global opioid crisis, development of GLP-1RA is an important research goal [106]

[DOI] [PubMed] [Google Scholar] 252.Gault V.A., Parker J.C., Harriott P., Flatt P.R., O'Harte F.P

2000;278(6):G94651

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An early RCT in 44 patients with obesity and subclinical binge eating showed that liraglutide was better than diet and exercise alone in reducing binge-eating scores at 12 weeks 220 , but a later investigation of 27 adults with BED comparing liraglutide against placebo did not find any differences in the number of binging episodes over 17 weeks 218