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STARDUST: Effects of the Glucagon Like-peptide 1 (GLP-1) Receptor Agonist Liraglutide on Lower Limb Perfusion in People With Type 2 Diabetes and Peripheral Artery Disease: a Randomized Controlled Trial

Muscle preservation requires resistance training and adequate protein intake

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95%CI 0.86-5.30

For most patients, sustained cardiometabolic benefit will require long-term, continuous use, making one-time or short-term coverage insufficient

95% CI, 1.03-1.11), though not NAION, over a 2-year follow-up period