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This aligns with the hypothesis that greater weight loss leads to superior cardiovascular benefits, reinforcing the potential of Tirzepatide in hypertensive patients with obesity

Wonder to what degree strength training was part of the protocol which should be the standard of care for those on GLP1

Shares in the maker of weight-loss drug Zepbound and diabetes treatment Mounjaro surged 5% in early trading and have gained more than 60% since the start of the year.

Most people begin noticing appetite changes within days of starting compounded semaglutide, with measurable weight loss typically appearing in weeks 2-4

Jardiance (empagliflozin) is used to treat type 2 diabetes, chronic kidney disease and reduce the risk of heart failure and cardiovascular disease

Additionally, several key clinical trial readouts delivered compelling data across multiple indications, for example (see Figure 1): Semaglutide: STEP-HFpEF (functional benefits in HFpEF), STEP-9 (pain reduction in knee osteoarthritis), STEP-10 (reversion to normoglycaemia in pre-diabetic, obese patients), ESSENCE (resolution of MASH, improvement in fibrosis) Tirzepatide: SUMMIT (risk reduction in HFpEF outcomes
