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The glucagon/GLP-1 agonistic effect of servodutide is similar to retatrutide, but servodutide lacks the GIP agonist activity of retatrutide

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Although GLP-1RAs can reduce body weight by 15%25% in controlled settings, real-world adherence is limited, and nearly 70% of patients experience weight regain after discontinuation, raising the risk of long-term pharmacological dependence ( Looking ahead, the future of GLP-1based therapy will depend on addressing safety concerns, improving long-term adherence, and expanding clinical indications

Akkermanisa Muciniphila is a type of beneficial bacteria that comprises up to 4% of the gut microbiome in healthy people