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Retatrutide is an investigational peptide developed by Eli Lilly and currently undergoing Phase 3 clinical trials

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doi:10.1016/j.diabres.2021.108737 Gatto A, Liu K, Milan N, Wong S

Previous studies have demonstrated that GLP-1 antagonists protect renal function from inflammation and oxidative stress-induced kidney damage in settings of acute kidney injury (48,49) and CKD, mainly through the suppression of DPP4 activity (16)

However, for medications with a narrow therapeutic index , such as digoxin, closer monitoring is necessary
