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N Engl J Med 381(7):637646 Pfeffer MA, Claggett B, Diaz R, Dickstein K, Gerstein HC, Kber LV et al (2015) Lixisenatide in patients with type 2 diabetes and acute coronary syndrome

The limited treatment landscape has created significant interest in repurposing existing drugs, particularly glucagon-like peptide-1 (GLP-1) receptor agonists, which address multiple metabolic pathways implicated in fatty liver disease

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This study did not include animal research, clinical trials, or the use of plants

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If patients have a severe obesity-related complication including but not limited to hypertension, type 2 diabetes, CVD, dyslipidemia and a BMI of 27 mg/kg 2 or greater, then concurrent initiation of weight-loss medication with lifestyle interventions can be considered, according to the guideline