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and enhance the immunity of elderly mice [37]

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Note: animal studies indicate that high doses of DPP-4 inhibitors & GLP-1 agonists cause expansion of cells of the pancreatic ductal glands and can cause premalignant pancreatic intraepithelial lesions (PanIN) that have the potential to progress to pancreatic adenocarcinoma

Survodutide Research# Key trials include the obesity Phase 2 (Lancet Diabetes & Endocrinology, 2024, 18.7% weight loss), MASH Phase 2 (NEJM, 2024, 62% MASH resolution), SYNCHRONIZE-1/2 (Phase 3, obesity, fully enrolled), and LIVERAGE (Phase 3, MASH, ongoing)