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In this study we investigated the target occupancy of the dual agonist SAR425899 at the GLP1R in pancreas and GCGR in liver by Positron Emission Tomography/Computed Tomography (PET/CT)
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A weekly dose of semaglutide, the key ingredient in blockbuster medications Ozempic and Wegovy, helped seven out of 10 patients newly diagnosed with type 1 diabetes stop taking insulin after three to six months in a small study.

New real-world research presented at the AAAAI Annual Meeting suggests that glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may significantly reduce asthma exacerbations in overweight and obese adults without diabetes pointing to a potential new therapeutic strategy for a difficult-to-treat population.