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Serious adverse events reported in temporal association with GLP-1 RA exposure included anaphylaxis with bronchospasm (n=4 cases), acute eosinophilic pneumonia (n=1), perioperative aspiration pneumonitis or pneumonia (multiple perioperative cases across two cohort studies and one case series), acute respiratory distress syndrome (ARDS

GLP-1 probiotics may offer microbiome support during GLP-1 therapy, but safety depends on individual microbial composition, concurrent medications, and gastrointestinal baseline