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doi: 10.1016/j.phrs.2022.106448

Since it has an additional mechanism compared to Januvia alone, it might be prescribed when blood sugar is not adequately controlled by monotherapy or as part of a multiple drug regimen for better control of blood glucose levels

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Avoid frequent temperature changes (e.g., repeated removal from the fridge)

however, rarity of SIS events calls for a cautious interpretation of our results

The ACCORD trial ended its intensive therapy early, after 3.5 years, because of a significant increase in deaths in the intensive-therapy group
