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Aetna plans that do cover Zepbound for weight loss require patients to meet particular criteria to get coverage

Indication bias (patients prescribed GLP-1 agonists may have underlying risk factors for autoimmune disease)

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This represented the largest weight reduction observed in any pharmacological trial at the time of publication, exceeding the published Phase 3 data for both semaglutide (STEP 1: 14.9%, Wilding et al., 2021) and Tirzepatide (SURMOUNT-1: 22.5%, Jastreboff et al., 2022) at comparable timepoints

It includes everything you do physically that is not structured exercise: walking, fidgeting, standing, cleaning, climbing stairs, carrying groceries

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