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European regulators have determined that Ozempic and similar semaglutide-based drugs increase the risk of a rare vision disorder that can cause vision loss and blindness.

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UK approval expected late 2026.

Since tirzepatide is a dual GLP1R/GIPR agonist, the interpretation is compelling: GIP receptor activation normally buffers the nausea-inducing effects of GLP-1 agonism, and when that buffer is genetically impaired, the GLP-1 component goes unchecked

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Hold the syringe upright (needle tip up) and gently tap the syringe to move any air bubbles to the top