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Circadian GLP-1 Secretion in mice is dependent on the intestinal microbiome for maintenance of diurnal metabolic homeostasis

Kidney Disease: Improving Global Outcomes CKDWG

According to current product labels, use of the GLP-1-based therapeutics should be discontinued 2 months before conception, as well as during pregnancy and lactation

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Kirkegaard H, Bliddal M, Stvring H, Rasmussen KM, Gunderson EP, Kber L, et al

The tissue was then digested for 15 min in a 37 C shaking water bath incubator using 5 ml of 100 U/ml collagenase type I (Sigma) in Basal Medium Eagle (Thermo Fisher Scientific) and supplemented with 1% BSA, 26.4 mM N a HCO 3 , and 10 mM HEPES (pH 6.9)