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(8) Excess body weight increases the mechanical load on weight-bearing joints, accelerating cartilage wear and joint degeneration, and contributing to a pro-inflammatory state that further exacerbates joint damage

Compared to control, significant reductions in intracranial pressure were seen acutely at 2.5 h and 24 h, but also at 12 weeks [101]

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Do not discontinue semaglutide without medical guidance