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So, Mounjaro unlike Wegovy has glucose-dependent insulinotropic Polypeptide (GIP) in addition to Glucagon-Like Peptide-1 (GLP-1)
PMC 8959203
The decrease in activity causes fewer amounts of hormones and peptides to be produced by the thymus
In the MASH liver trials, discontinuation studies are still limited, but early data suggests liver enzyme improvements and histological gains are not maintained without ongoing treatment
doi: 10.1016/S0140-6736(17)33102-1
