trt and glp 1 GLP-1 Together: Safety, Dosing, Benefits Tirzepatide and Testosterone: Low T,
Description
It slows gastric emptying, communicates with the brains appetite control centre to reduce hunger, and improves blood sugar levels

Bhatt DL, Szarek M, Pitt B, et al

Gallagher AM, Dedman D, Padmanabhan S, Leufkens HGM, de Vries F
"The GLP-1R monoagonists displayed a significant positive correlation between Css [circulating concentration] and nausea, which is not observed for the GIPR/GLP-1R dual-agonist." Jonathan D

Beyond current indications, Alberta Blue Cross identifies potential future expanded uses including: Metabolic dysfunction-associated steatohepatitis (MASH) [Source: ab.bluecross.ca/plans/group/drug-pipeline-2026.php] Obstructive sleep apnea (OSA) [Source: ab.bluecross.ca/plans/group/drug-pipeline-2026.php] The insurer characterizes the developing GLP-1 pipeline as robust, with treatments described as more effective, broader in use, and longer between doses [Source: ab.bluecross.ca/plans/group/drug-pipeline-2026.php]

DOI:10.1093/eurheartjsupp/suae011
