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Cell Metab 29 , 221228 (2019)

GLP-1 medications and testosterone in men with obesity

Severe gastrointestinal disease may worsen with incretin therapy

Data from the pivotal STEP (Semaglutide Treatment Effect in People with obesity) clinical trials , which involved over 4,500 participants, showed that headache was among the ten most frequently reported adverse events

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By intervening in this area, they help delay the neural cues so that recipients (1) dont feel hungry as often and (2) feel satiated for longer when they do eat