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2024Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity: the surmount-4 randomized clinical trial

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Metabolic function is in flux, habits are still forming and without the right support, weight regain is common

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As the beta cell secretory response to high levels of blood glucose is augmented by GLP-1, so is the paracrine inhibition of glucagon secretion by beta cell secretory products [49]