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Additionally, as patients lose fat mass (which provides insulation), core temperature homeostasis shifts
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On the contrary, a small study of fewer than 10 obese patients who took berberine three times a day for three months found their average weight loss with berberine was just around 5 pounds

10.1017/S0007114516003858 61

So good patient engagement and regular review is critical for maintaining engagement and compliance. To help support GPs in their delivery of care to patients with severe mental illness, the Psychological Medicine Chair said a multidisciplinary approach is needed

These medications can be expensive, and not all insurance plans cover them, which may limit your access
