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GLP-3 might fit into combination strategies by providing complementary metabolic effects not fully achieved by GLP-1 alone, potentially enhancing specific aspects like fat oxidation or metabolic flexibility, possibly allowing lower doses of each peptide with fewer side effects, or addressing metabolic resistance that can develop with single-peptide approaches

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[DOI] [PMC free article] [PubMed] [Google Scholar] Nikolaidis L.A., Elahi D., Shen Y.-.T., Shannon R.P
GLP-1 weight loss is up to 35% muscle mass loss GLP-1 weight loss can be 20% to 35% loss of lean tissue instead of fat

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Stronger is not always the same as better for you. Which medication causes the most weight loss
