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Tirzepatide should be administered on the same day each week, with injections into the abdomen, thigh, or upper arm

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using them for weight loss alone is off-label

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Begin liraglutide approximately one week after your last tirzepatide injection to allow levels to decline

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Last reviewed: June 9, 2026 Last updated: June 9, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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The combination of tirzepatide with consistent resistance training and adequate protein intake creates a powerful body recomposition effect

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