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OFA also submitted a comment to the FDA that argues the semaglutide shortage remains ongoing: OFA conservatively estimates that roughly 80 million prescriptions for semaglutide were fulfilled with compounded semaglutide in the last 12 months, inclusive of 503A pharmacy compounders and 503B outsourcing facilities

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Rizzo, M.R

The shift to off-label prescribing of GLP-1 RAs has impacted product availability for patients with type 2 diabetes

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Many people with T2DM are left without their essential medications and antidiabetic regimes had to be altered [71]