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(Note The ATTAIN-1 trial is investigating the efficacy and safety of once daily oral orforglipron in adult participants with obesity or overweight with weight-related comorbidities.) Orforglipron Orforglipron is an orally bioavailable, non-peptide agonist of the GLP-1 receptor

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Ellingsgaard H, Seelig E, Timper K et al (2020) GLP-1 secretion is regulated by IL-6 signalling: a randomised, placebo-controlled study

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