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For users this could segway into an expansion of the private market and for payers this could provide an affordable entry point for public reimbursement

Significance statement ![Figure][1] ### Competing Interest Statement The authors have declared no competing interest

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After a few years of injectable dominance, oral formulations are emerging as a game-changer for adherence and ease of use thanks to their lack of cold-chain requirement, but also a game-changer for their ability to unlock the long-term maintenance opportunity [14]