glp receptor 1 agonists Trends in the Development of GLP-1 GLP-1 receptor agonists show promise

Like all GLP-1 treatments, it only works alongside diet and activity changes

doi: 10.3389/fendo.2023.1121303 [DOI] [PMC free article] [PubMed] [Google Scholar] 28

This demonstrates the huge revenue driver Lilly could have through orforglipron if the drug gets approved

[DOI] [PMC free article] [PubMed] [Google Scholar] 230.Rodriguez L.A., Finertie H., Neugebauer R.S., Gosiker B., Thomas T.W., Karter A.J., Gilliam L.K., Oshiro C., An J., Simonson G., et al

These data were confirmed in a pooled analysis of the two trials with a reduction of CRP level with semaglutide of 43% vs 10% with placebo (OR 0.64, 95% C.I

In April 2026, Canada approved a generic version of semaglutide see our Generic Ozempic Canada article for more details