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For example, one clinical trial reported that 15.2 percent of participants experienced headaches after higher-dose semaglutide, compared to 12.2 percent of participants receiving a placebo (an inactive treatment)

Official Government Resources: Ministry of Health & Family Welfare: [MoHFW Official Website]( Central Drugs Standard Control Organization (CDSCO): [CDSCO Official Website]( Gazette Notifications and Drug Regulatory Updates: [e-Gazette of India]( The decision was taken under Section 26A of the Drugs and Cosmetics Act, 1940, after recommendations from expert committees and the Drugs Technical Advisory Board (DTAB)

Curb cravings and regulate appetite*

A 2025 study found that 40% of semaglutide users exhibited increased residual gastric content versus only 3% of non-users
[63] first reported the existence of G protein-coupled receptor (GPCR) GLP-1R in human hepatocytes in 2010, and provided evidence to prove the direct effects of GLP-1 protein on cells

Dosage and Titration: Semaglutide dosage for weight loss involves increasing the dose over 5 months until achieving the maximum of 2.4mg per week as opposed to reaching the maximum dose with five weeks of liraglutide therapy
