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72,73 In the double-masked 96-week PHOTON (Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease) trial, 74 patients with center-involved DME were randomized to receive aflibercept 8 mg every 12 or 16 weeks after three monthly doses or aflibercept 2 mg every 8 weeks after five monthly doses

Nielsen erklrt: Zuknftige Studien mssen den Grund fr die Verschreibung dieser Medikamente bercksichtigen, da sich die Risiken bei Frauen, die GLP-1-RA gegen Diabetes einnehmen, von denen unterscheiden, die sie zur Gewichtsreduktion anwenden

In addition, the SUSTAIN trials excluded patients with recent medication changes and comorbidities, such as heart failure and a history of pancreatitis, among others 1116,3133