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We initialize both the number and centroid of clusters using a density-based clustering algorithm called Hierarchical Density-Based Spatial Clustering of Applications with Noise (HDBSCAN) first and fine-tune the assignment of discussions into the appropriate topics using KMeans clustering

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Also, a multicenter, double-blind clinical trial demonstrated that once-weekly TRZ for 72 weeks at a dose of 10 mg and 15 mg was safe and well-tolerated compared to other incretin-based treatments for weight reduction (Jastreboff et al

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